Ocular manifestations in infants exposed to the Zika virus: an integrative review

Authors

DOI:

10.52832/jesh.v3i1.165

Keywords:

Eye, Zika virus, Congenital abnormalities

Abstract

Zika virus belongs to the Flavivirus genus and is transmitted to humans, mainly by the Aedes aegypti mosquito. The infection is usually asymptomatic, but it can manifest itself with serious repercussions in newborns who had contact with the viral strain during the gestational period. The set of clinical characteristics presented by the children was named Congenital Zika Syndrome, in which microcephaly and visual alterations are quite common. This work aims to verify in the literature the damage caused to the organs of human vision in children exposed to the Zika virus during the gestational period and to establish the pathogenic relationship of this syndrome. This is an integrative review of the literature carried out at the National Library of Health (BVS), at the National Library of Medicine (PubMed) and at Scientific Electronic Library Online (SciElo), using the descriptors: Infecção por Zika vírus, Oftalmopatias, Anormalidades congênitas and their correlates in English. Thirteen articles were chosen for this review. Hypoplasia of the second pair of cranial nerves, choriorectal atrophy, macular scarring, iris coloboma, congenital cataracts, glaucoma and microphthalmia are among the most prevalent ocular lesions in Congenital Zika Syndrome. Despite this link, it is still possible to infer that when the infection occurs in the first half of the gestational period, the risk becomes greater.

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Author Biographies

Jefferson Pereira Sarmento, Centro Universitário Santa Maria - UNIFSM

Estudante de Medicina. Centro Universitário Santa Maria (UNIFSM), Cajazeiras, Paraíba, Brasil.

Ricardo Lourenço Coelho, Centro Universitário Santa Maria - UNIFSM

Especialista em Oftalmologia pelo Hospital de Olhos Leiria de Andrade (HOLA). Professor do Centro Universitário Santa Maria (UNIFSM), Cajazeiras, Paraíba, Brasil.

Almi Soares Cavalcante, Centro Universitário Santa Maria - UNIFSM

Especialista em Pediatria pela Sociedade Brasileira de Pediatria (SBP). Professor do Centro Universitário Santa Maria (UNISM), Cajazeiras, Paraíba, Brasil.

Thaise de Abreu Brasileiro Sarmento, Centro Universitário Santa Maria - UNIFSM

Mestra em Sistemas Agroindustriais pela Universidade Federal de Campina Grande (UFCG). Especialista em Pediatria pelo Hospital Universitário Osvaldo Cruz (HUOC). Professora do Centro Universitário Santa Maria (UNIFSM), Cajazeiras, Paraíba, Brasil.

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Published

13/03/2023

How to Cite

Sarmento, J. P., Coelho, R. L., Cavalcante, A. S., & Sarmento, T. de A. B. (2023). Ocular manifestations in infants exposed to the Zika virus: an integrative review. Journal of Education, Science and Health – JESH, 3(1). https://doi.org/10.52832/jesh.v3i1.165

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Section

REVISÕES DA LITERATURA