FACTORS ASSOCIATED WITH MORTALITY AND TIME TO ANTIBIOTIC INITIATION IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA

Authors

DOI:

https://doi.org/10.52832/jesh.v6i2.680

Keywords:

Mortality, Corporate Sustainable, Prognosis, Antibiotic therapy., Treatment

Abstract

Community-acquired pneumonia (CAP) is a significant cause of morbidity and mortality, especially in vulnerable populations such as the elderly and individuals with comorbidities. Among the prognostic factors, the time to initiation of antibiotic therapy stands out as a crucial element in the clinical evolution of these patients. The objective of this study is to analyze, in the scientific literature, the main factors associated with mortality and the time to initiation of antibiotic therapy in patients with CAP. This is a systematic literature review, carried out through a systematic search in the PubMed, SciELO, and Virtual Health Library (VHL) databases. Original studies published in the last 5 years, in English, Portuguese, and Spanish, that addressed factors related to mortality and the time to initiation of antibiotics in patients with CAP were included. The selection of studies was conducted in stages, with reading of titles, abstracts, and full texts, according to previously defined inclusion and exclusion criteria. The extracted data were analyzed descriptively and synthesized according to the main findings. The studies analyzed show that factors such as advanced age, presence of comorbidities, greater clinical severity at admission, and delay in initiating antibiotic therapy are significantly associated with increased mortality. Furthermore, care barriers and failures in early recognition of severity contribute to therapeutic delays. Early identification of factors associated with delayed initiation of antibiotic therapy and mortality is fundamental for optimizing the clinical management of CAP, potentially positively impacting outcomes and reducing mortality.

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Author Biographies

  • Namibia Pimenta Guevara, Universidade Federal do Rio de Janeiro

    Graduada em medicina pela Universidade Federal do Rio de Janeiro

  • Diego Mauricio Calegare Rodrigues, União das Faculdades dos Grandes Lagos

    Graduando em medicina pela União das Faculdades dos Grandes Lagos

  • Lucio Mauro Boaventura Latorre, Universidade do Estado do Pará

    Graduado em medicina pela Universidade do Estado do Pará. 

  • Isadora Vieira Peliano , Centro universitário Presidente Antônio Carlos (UNIPAC-JF)

    Graduando em medicina Centro universitário Presidente Antônio Carlos (UNIPAC-JF)

  • Daniela Senra Melo , Universidade Presidente Antônio Carlos

    Graduando em medicina pela universidade presidente Antônio Carlos 

  • Aline Aparecida Almeida Machado, Centro Universitário Presidente Antônio Carlos - Unipac

    Graduanda em medicina pela Centro Universitário Presidente Antônio Carlos - Unipac

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Published

02/05/2026

Issue

Vol. 6 No. 2 (2026): JESH (abr.-jun.)

Section

REVISÕES DA LITERATURA

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How to Cite

FACTORS ASSOCIATED WITH MORTALITY AND TIME TO ANTIBIOTIC INITIATION IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA. (2026). Journal of Education, Science and Health – JESH, 6(2). https://doi.org/10.52832/jesh.v6i2.680